The first modern asylum in Spain Historical milestone · Leganés, Área Metropolitana, Madrid Image of Leganés, not of the place itself. The National Asylum of Santa Isabel opened in the old palace of the marquises of Leganés and received its first forty-four patients in April 1852. It was the first state psychiatric establishment in the country. 28 de diciembre de 1851 Photo: FDV (CC BY-SA 3.0) What to see and do in Leganés